✦   Writer & Historian   ✦

Mark Honigsbaum

Medical Historian · Journalist · Author

About Me

Mark Honigsbaum

I am a writer and journalist specialising in the history and science of infectious disease. A regular contributor to The Observer and The Lancet, my books include a global history of malaria and a social history of the 1918 influenza pandemic, Living With Enza, which was nominated for the Royal Society Science Book of the Year in 2009.

In May 2019, six months before the novel coronavirus SARS-CoV-2 emerged in China, I published The Pandemic Century: 100 Years of Panic, Hysteria and Hubris, explaining why, despite more than a century of medical progress, pandemics continue to take us by surprise, spreading fear and conspiracy theories.

As well as writing for popular audiences, I am a medical historian and have been published in Medical History, Social History of Medicine, and the History and Philosophy of the Life Sciences.

Prior to becoming a full-time writer and researcher, I enjoyed a long career as an investigative reporter and feature writer at newspapers including the Evening Standard, The Independent on Sunday, The Observer and The Guardian. In 1996 my Channel 4 Dispatches exposé of the British intelligence services' involvement in re-arming the Argentine Navy after the Falklands War was shortlisted for the best current affairs documentary at the Royal Television Society Awards.

I write at Going Viral and am honorary fellow at UCL's Institute of Global Health.

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Books

"The good historian is like the giant of the fairy tale… wherever he catches the scent of human flesh, there his quarry lies."

— Marc Bloch
The Pandemic Century
The Pandemic Century: One Hundred Years of Panic, Hysteria and Hubris
New York: Norton; London: Hurst, 2019

Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet, despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. Named one of the best books of the year in "Health" by the Financial Times and an "Editor's Choice" by the New York Times.

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A History of the Great Influenza Pandemics
A History of the Great Influenza Pandemics: Death, Panic and Hysteria, 1830–1920
I.B. Tauris, 2014

Influenza was the great killer of the nineteenth and twentieth centuries. The so-called 'Russian influenza' epidemic killed about 1 million people across Europe in 1889–93. The Spanish flu of 1918, meanwhile, would kill 50 million people — nearly three percent of the world's population.

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Living with Enza
Living with Enza: The Forgotten Story of Britain and the Great Flu Pandemic of 1918
Palgrave Macmillan, 2009 · Nominated for Royal Society Science Book of the Year

Between the summer of 1918 and the spring of 1919 a deadly strain of influenza claimed the lives of 228,000 Britons. Worldwide the death toll from 'Spanish' influenza was simply unimaginable — between 50 million and 100 million dead.

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The Fever Trail
The Fever Trail: In Search of the Cure for Malaria
London: Macmillan; New York: Farrar Straus & Giroux, 2001

Malaria is a deadly parasitical infection with a vicious ability to mutate. This book retraces the extraordinary quest for quinine — the only cure before the twentieth century — through the Andes and the story of a miraculous tree that changed medicine forever.

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Valverde's Gold
Valverde's Gold: In Search of the Last Great Inca Treasure
New York: Farrar Straus & Giroux, 2004

In 1887, two British sailors set off across the Andes on a secret mission: to locate an immense hoard of Inca gold lost for hundreds of years in a remote mountain range above the Amazon. An adventure story that is also a meditation on obsession, myth, and the lure of lost worlds.

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Essays

Index on Censorship · April 2025

It is deeply troubling that the USA's new health secretary believes in conspiracy theories and is hostile towards modern medicine.

Engelsberg Ideas

Few events are as compelling as an epidemic. When sufficiently severe, an epidemic evokes responses from every sector of society, laying bare social and economic fault lines and presenting politicians with fraught medical and moral choices.

The Lancet · 2018

The Spanish influenza virus — or at least its viral offspring — have been circulating for 100 years, but it is only in recent years that histories of the pandemic have achieved a similar ubiquity in our culture.

Tortoise Media · March 2021

How can we commemorate grief on the scale of Covid-19? A year into the pandemic, the coronavirus has left a void in all our communities — a vacuum that cries out to be filled.

The Lancet · 2020

Examining the long-term health and societal consequences of pandemic disease — an issue that gained new urgency with the emergence of 'long Covid'.

The Lancet · 2019

In 2018, the WHO added 'Disease X' to its emergency priority list — recognising that a serious international epidemic could be caused by a pathogen currently unknown to science. How should we prepare for the truly unknown?

The Lancet · 2014

Ebola seems to draw on a familiar store of images and metaphors — of parasites and hot zones, desperate patients, and intrepid disease detectives. But which earlier epidemics does it echo, and what can the parallels tell us?

The Conversation

Around the world, vaccines are in retreat, shunned by populations who have never been exposed to the diseases that blighted their grandparents' generation — yet vaccines have saved more lives than almost any other intervention in medical history.

Science Direct · The Lancet

The history of antibiotics is usually told as triumph followed by tragedy. Only rarely do historians mention another miracle drug, gramicidin, and the Rockefeller researcher who discovered it.

QMul Emotions Blog · 2011

An exploration of how epidemic disease is imagined in popular culture — from Rise of the Planet of the Apes to our deepest fears about pandemic spread across a connected world.

Academic Articles

The Lancet · 2018
A centennial reassessment of the 1918 influenza pandemic and its enduring resonance in historical memory and epidemiological science.
The Lancet · 2020
An argument for greater clinical and epidemiological attention to the long-term consequences that follow major pandemic events.
The Lancet · 2019
An analysis of the WHO's 'Disease X' category, the epistemology of pandemic preparedness, and the challenge of unknown unknowns in infectious disease.
The Lancet · 2014
Situating the 2014 West African Ebola outbreak within the longer history of epidemic panic, cultural metaphor, and institutional response.
Social History of Medicine / The Lancet
An examination of how and why the AIDS pandemic generated rich cultural and artistic memorialisation while the 1918 influenza pandemic left comparatively faint emotional traces.
The Lancet
A historical reassessment of René Dubos, discoverer of gramicidin, and his prescient warnings about the limits of the antibiotic era.
History and Philosophy of the Life Sciences
Ecology, Environment and the Origins of Disease Ecology
Drawing on a Wellcome Trust postdoctoral fellowship, this research examines the intellectual origins of disease ecology and environmental approaches to infectious disease history.

Journalism

The Observer / The Guardian
A new film about the origins of Covid-19 tells how rightwing conspiracy theorists pushed the lab-leak theory to their own ends, suppressing the work of real scientists. — The Observer, April 2025
Pandemics end in different ways but it's never quick and never neat. — Observer, October 2020
How the terminal sugar molecules on our cells regulate our interactions with pathogens and help make us who we are. — The Guardian, December 2023
We all cry, but what biological function do tears serve — and why are humans the only species that shed tears of sorrow and joy? — The Guardian, April 2013
It was on a routine visit to the doctor that my GP uttered the phrase every middle-aged man dreads: "Your blood pressure is a little raised." — The Guardian, January 2012
In 2006, I accidentally triggered a conspiracy theory about the London tube bombings — a preview of how the internet would make us more susceptible to rumour. — The Guardian, June 2006
A 2006 interview with a nineteen-year-old Murray — already tipped as the future of British tennis — on Dunblane, his parents' separation, and carrying a nation's hopes. — The Observer, June 2006
The Telegraph
A compound from the bark of the Chilean soapbark tree is revolutionising vaccine adjuvants — but because of climate change and illegal logging, bark supplies are running low, jeopardising global efforts to eliminate malaria. — The Telegraph
Other Publications
The Spectator, August 2020
A long-form report on the final stages of the West African Ebola epidemic. — Mosaic Science
As Germany succumbed to antisemitism in the 1930s, Ernst Leitz, owner of Leica cameras, defied the Nazis by helping Jewish employees emigrate to the United States.
A re-examination of Diana's fraught — and often willing — relationship with the British tabloid press. — The Spectator, September 1997

Going Viral

Going Viral

The history, science and culture of infectious disease — plus a little politics and poetry. A reader-supported Substack publication by Mark Honigsbaum.

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Recent writing on Going Viral

Peter Mandelson, Jeffrey Epstein, and the Culture of Deference
Why it took the Epstein files for Labour's Prince of Darkness to finally face a reckoning.
RFK Jr and the Republican War on Public Health
A man whose cousin called him a "predator" and his vaccine views "dangerous and wilfully misinformed" is now America's health secretary.
Wendy Barclay: Britain's Leading Flu Virologist
A conversation with the Imperial College virologist on what the latest flu science tells us about the next pandemic threat.
The Russian Flu of 1889: A Victorian Pandemic Revisited
Before Spanish flu, there was the Russian flu — and its echoes are everywhere in our current pandemic politics.
Read all posts on Substack →